Ninety percent of the world's youth live in Africa, Latin America and the developing countries of Asia. Despite this, the field of Youth Studies, like many others, is dominated by the knowledge economy of the Global North. To address these geopolitical inequalities of knowledge, The Oxford Handbook of Global South Youth Studies offers a contribution from Southern scholars to remake Youth Studies from its current state, that universalizes Northern perspectives, into a truly Global Youth Studies. Contributors from across the Global South-including from Diaspora, Indigenous and Aboriginal communities-locate and define 'the Global South'; articulate the necessity of studying Southern lives to enrich, reinterpret, legitimate, and offer symmetry to youth studies; and use Southern theory to do so.