000			01776nmm a2200193Ia 4500
008			220920s9999||||xx |||||||||||||| ||und||
020			_a9780511541520
082			_a579.316 5 _bH397H
100			_aHensel, M. _eAuthor _lEnglish _92241
245		0	_aHorizontal Gene Transfer in the Evolution of Pathogenesis _c/ edited by M. Hensel and H. Schmidt. _h[Electronic Resource]
260			_aCambridge _b: Cambridge University Press, _c2008
300			_axvii, 356p.
520			_aHorizontal gene transfer is a major driving force in the evolution of many bacterial pathogens. The development of high-throughput sequencing tools and more sophisticated genomic and proteomic techniques in recent years has resulted in a better understanding of this phenomenon. Written by leading experts in the field, this edited volume is aimed at graduate students and researchers and provides an overview of current knowledge relating to the evolution of microbial pathogenicity. This volume provides an overview of the mechanisms and biological consequences of the genome rearrangements resulting from horizontal gene transfer, in both prokaryotes and eukaryotes, as well as overviews of the key mobile genetic elements involved. Subsequent chapters focus on paradigms for the evolution of important bacterial pathogens, including Salmonella enterica, Streptococcus pneumoniae, and Staphylococcus aureus. The influence of socioeconomic parameters in the dissemination of transferable elements, such as antibiotic resistant genes in bacteria, is also discussed.
650			_aGenetics _91106
650			_aMicrobiology And Immunology _92242
700			_aSchmidt, H. _i[Editor] _92243
856			_uhttps://doi.org/10.1017/CBO9780511541520 _qPDF _yClick to Access the Online Book
942			_cEBK _nYes
999			_c12393 _d12393