Development Of Biocompatible Super Hydrophobic Coating On Degradable Magnaesium Implants (Record no. 14781)

MARC details
000 -LEADER
fixed length control field 02613nam a22001697a 4500
082 ## - DEWEY DECIMAL CLASSIFICATION NUMBER
Classification number 620.112
Item number S531D
100 ## - MAIN ENTRY--AUTHOR NAME
Personal name Sharma,Chirag
245 ## - TITLE STATEMENT
Title Development Of Biocompatible Super Hydrophobic Coating On Degradable Magnaesium Implants
Statement of responsibility, etc by Chirag Sharma
260 ## - PUBLICATION, DISTRIBUTION, ETC. (IMPRINT)
Place of publication IIT Jodhpur
Name of publisher Department of Metallurgical & Materials Engineering
Year of publication 2020
300 ## - PHYSICAL DESCRIPTION
Number of Pages xiii,56p.
Other physical details HB
520 ## - SUMMARY, ETC.
Summary, etc Traditional medical implants are designed to stay in body permanently which cause several complication and allergies in long run. This has attracted the focus on development of biodegradable metallic implant which will wash off from body once their purpose is served. In this context the magnesium based biodegradable implant has drawn considerable attention in recent year due to their superior biocompatibility. However, their high degradation rate and lower mechanical strength poses a challenge in their wide spread application. It losses it mechanical integrity before bone tissue is healed to an acceptable level. In present work a biocompatible liquid repellent super hydrophobic coating is developed on casted Mg4Zn alloy to address the high degradation rate. One set of sample is pretreated with saturated solution of sodium carbonate to form a passive layer of magnesium carbonate and other set of samples are coated with hydroxyapatite powder using plasma spraying which improve the cell attachment (osseointegration) behavior. Polydimethylsiloxane(PDMS) is used as low surface energy material to create super hydrophobic coating. The corrosion rate of hydroxyapatite coated sample has reduced from 1.24*10-2 gm/mm2year to 6.1*10-5 gm/mm2year. The physical appearance of sample show no delamination of coating is observed even after 7 days of immersion in simulated body fluid. The hydrogen evolution data for the same sample show that total volume of H2 gas liberation during corrosion is reduced from 115.7 ml to 21.0 ml. This help in avoid hydrogen gas pockets which can be fatal nearby cell if not displaced in time. Similarly, for chemical conversion coated sample the corrosion rate is reduced from 1.05*10-2 gm/mm2year to 2.1*10-3 gm/mm2year. Present research open gate for various potential application of super hydrophobic coating in medical industries and gives a prospective to approach the future problem by keeping in mind the hydrophobic coating as tool in available in box. <br/>
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical Term Biocompatible Super Hydrophobic Coating
Topical Term MTech Theses
Topical Term Department of Metallurgical & Materials Engineering
700 ## - ADDED ENTRY--PERSONAL NAME
Personal name Kashyap. B.P.
942 ## - ADDED ENTRY ELEMENTS (KOHA)
Koha item type Thesis
Holdings
Withdrawn status Lost status Damaged status Not for loan Collection code Permanent Location Current Location Shelving location Date acquired Full call number Accession Number Price effective from Koha item type
      Not For Loan Reference S. R. Ranganathan Learning Hub S. R. Ranganathan Learning Hub Course Reserve 2024-02-05 620.112 S531D TM00195 2024-02-05 Thesis