MARC details
| 000 -LEADER |
|---|
| fixed length control field |
03124nmm a22003495i 4500 |
| 005 - DATE AND TIME OF LATEST TRANSACTION |
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| control field |
20230705150638.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION |
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| fixed length control field |
100301s2005 xxu| s |||| 0|eng d |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER |
|---|
| International Standard Book Number |
9780387239231 |
| -- |
978-0-387-23923-1 |
| 082 ## - DEWEY DECIMAL CLASSIFICATION NUMBER |
|---|
| Classification number |
612.8 |
| Edition number |
23 |
| 245 ## - TITLE STATEMENT |
|---|
| Title |
Neurodegeneration and Prion Disease |
| Medium |
[electronic resource] / |
| Statement of responsibility, etc. |
edited by David R. Brown. |
| 250 ## - EDITION STATEMENT |
|---|
| Edition statement |
1st ed. 2005. |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. |
|---|
| Place of publication, distribution, etc. |
New York, NY : |
| Name of publisher, distributor, etc. |
Springer US : |
| -- |
Imprint: Springer, |
| Date of publication, distribution, etc. |
2005. |
| 300 ## - PHYSICAL DESCRIPTION |
|---|
| Extent |
XV, 473 p. |
| Other physical details |
online resource. |
| 505 ## - FORMATTED CONTENTS NOTE |
|---|
| Formatted contents note |
Neuropathology of Transmissible Spongiform Encephalopathies (Prion Diseases) -- Central Pathogenesis of Prion Diseases -- Hereditary Prion Protein Amyloidoses -- Mouse Behavioural Studies and What They Can Teach Us about Prion Diseases -- Electrophysiological Approaches to the Study of Prion Diseases -- Prion Protein, Prion Protein-Like Protein, and Neurodegeneration -- Oxidative Stress and Mitochondrial Dysfunction in Neurodegeneration of Transmissible Spongiform Encephalopathies (TSEs) -- Mechanisms of Prion Toxicity and Their Relationship to Prion Infectivity -- A Stone Guest on the Brain: Death as a Prion -- Molecular Mechanisms Mediating Neuronal Cell Death in Experimental Models of Prion Diseases, in vitro -- Processing and Mis-Processing of the Prion Protein: Insights into the Pathogenesis of Familial Prion Disorders -- Signaling Pathways Controling Prion Neurotoxicity: Role of Endoplasmic Reticulum Stress-Mediated Apoptosis -- Cell Culture Models to Unravel Prion Protein Function and Aberrancies in TSE -- Insights into the Cellular Trafficking of Prion Proteins -- The Molecular Basis of Prion Protein-Mediated Neuronal Damage -- Conclusion: Intervention, the Final Frontier. |
| 520 ## - SUMMARY, ETC. |
|---|
| Summary, etc. |
This volume provides an in-depth overview from world experts on prion disease. These fatal diseases include Creutzfeldt-Jakob disease, chronic wasting disease in deer, scrapie of sheep, bovine spongiform encephalopathy (mad cow's disease) of cattle and related diseases. Understanding what causes neuronal death in these diseases is essential to both preventing and curing them. The most recent advances in understanding neuronal death in prion diseases are presented. Prion diseases serve as an experimental model for all neurodegenerative conditions. This book will provide understanding of neurodegeneration and provide an up-to-date record of the state of the art for other specialists and non-specialists in related fields. |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name entry element |
Neurosciences. |
| 9 (RLIN) |
20502 |
|
|---|
| Topical term or geographic name entry element |
Biomathematics. |
| 9 (RLIN) |
20503 |
|
|---|
| Topical term or geographic name entry element |
Neurology . |
| 9 (RLIN) |
20504 |
|
|---|
| Topical term or geographic name entry element |
Biochemistry. |
| 9 (RLIN) |
20505 |
|
|---|
| Topical term or geographic name entry element |
Veterinary medicine. |
| 9 (RLIN) |
20506 |
|
|---|
| Topical term or geographic name entry element |
Medicine-Research. |
| 9 (RLIN) |
20507 |
|
|---|
| Topical term or geographic name entry element |
Biology-Research. |
| 9 (RLIN) |
20508 |
|
|---|
| Topical term or geographic name entry element |
Neuroscience. |
| 9 (RLIN) |
20509 |
|
|---|
| Topical term or geographic name entry element |
Mathematical and Computational Biology. |
| 9 (RLIN) |
20510 |
|
|---|
| Topical term or geographic name entry element |
Neurology. |
| 9 (RLIN) |
20504 |
|
|---|
| Topical term or geographic name entry element |
Biochemistry. |
| 9 (RLIN) |
20505 |
|
|---|
| Topical term or geographic name entry element |
Veterinary Science. |
| 9 (RLIN) |
20511 |
|
|---|
| Topical term or geographic name entry element |
Biomedical Research. |
| 9 (RLIN) |
20512 |
| 700 ## - ADDED ENTRY--PERSONAL NAME |
|---|
| Personal name |
Brown, David R. |
| Relator term |
editor. |
| Relationship |
edt |
| -- |
http://id.loc.gov/vocabulary/relators/edt |
| 9 (RLIN) |
20513 |
| 856 ## - ELECTRONIC LOCATION AND ACCESS |
|---|
| Uniform Resource Identifier |
<a href="https://doi.org/10.1007/b103635">https://doi.org/10.1007/b103635</a> |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) |
|---|
| Koha item type |
e-Book |
